Repair-seq data browser

Parallel coordinates plot of log₂ fold changes in intended prime edit frequencies

Lines represent individual CRISPRi sgRNAs, and columns represent distinct screens. Lines plots the log₂ fold change in frequency of the intended substitution prime edit in the presence of each sgRNA across 10 different screen conditions.

Search: Highlight on hover:

Identifying lines

Mouseover a line to highlight and label it.

Searching for specific genes

To search for specific sgRNAs, type into the search box and press enter.
Matching sgRNAs will be highlighted and will populate the table below. Mouseover rows in the table to identify corresponding lines.

Brushing data ranges

Click and drag on an axis to "brush" a data range, highlighting sgRNAs with values in this range.
Once a brush exists, click and drag on its edge to resize it, or click and drag on its middle to move it.
Brush multiple axes to apply multiple constraints.
Click outside of a brush on an axis to clear that brush. Click the "Clear all constraints" button to remove all brushes.

Reordering axes

Click and drag on an axis label to reorder axes.

Zooming in and out

With the mouse positioned over an axis, scroll the mouse wheel to zoom in and out.

About

Plots built using D3.js, including adapted code from github.com/syntagmatic/parallel-coordinates, bl.ocks.org/mostaphaRoudsari/b4e090bb50146d88aec4, and bl.ocks.org/jasondavies/1341281.